Sanofi Expands Cancer Treatment Offerings with $9.5 Billion Blueprint Acquisition

Cambridge, Monday, 2 June 2025.
Sanofi’s acquisition of Blueprint Medicines for $9.5 billion boosts its oncology and precision medicine portfolio, marked by a 27% surge in Blueprint’s stock.
Sanofi’s Strategic Acquisition Move
In a landmark agreement announced on June 2, 2025, Sanofi has committed to acquiring Blueprint Medicines Corporation for a total value of up to $9.5 billion. The deal underscores Sanofi’s strategic thrust into expanding its portfolio within the realms of rare immunology diseases and oncology, making it the most significant acquisition by a European healthcare company this year [1][2].
Financial Details and Motivations
Sanofi plans to pay $129 per share in cash, which amounts to approximately $9.1 billion in equity value. Additionally, Blueprint’s shareholders will receive contingent value rights (CVRs) that could potentially bring the transaction’s total value to $9.5 billion upon achieving specific milestones in developing and regulatory success with the drug BLU-808 [1][3][4]. The premium on Blueprint’s stock is approximately 33% over its closing price on 30 May 2025 [2].
Implications for the Biopharma Sector
This acquisition is poised to significantly enhance Sanofi’s capabilities in precision medicine, a field that is rapidly shaping the future of oncology treatments. Blueprint Medicines is renowned for its advanced drug Ayvakit, the only approved medication for advanced and indolent systemic mastocytosis, and the acquisition positions Sanofi to advance its competitive stance in treating both rare and common immune diseases [4][5].
Timeline and Future Prospects
The transaction, which remains subject to regulatory and shareholder approvals, is expected to close in the third quarter of 2025. Sanofi anticipates that the acquisition will become accretive to its gross margin and business operating income by 2026. Meanwhile, the successful integration of Blueprint’s pipeline is crucial for Sanofi to bolster its presence in the immunology market, leveraging newly acquired innovations to push forward its mission of delivering life-changing medicines [2][3].